Medical Studies Prove The Extensive Damage LSD Does To The Body & Mind
In a recent series of Hubs on LSD and the effects on pregnant women I was challenged to prove my statements that LSD was extremely harmful. Well... here we go.
Of nine studies in vitro, six have indicated some degree of induced chromosomal breakage after exposure to LSD; three failed to confirm these results. The damage, when found, was generally of the chromatid type, arising during or after DNA synthesis.
The results of early chromosome studies suggested that true genetic damage might be a consequence of LSD exposure. The comprehensive evidence from studies on drosophila indicates no mutagenic effect from 0.28 to 500 microg of LSD per milliliter and a definite mutagenic effect from 2,000 to 10,000 microg/ml; this is consistent with a threshold response or a sigmoid dose-effect relation.
Circular dichroism experiments suggested that the specific mechanism of action of LSD on DNA may be a direct interaction resulting in conformational changes in the DNA helix.
Early chromosomal studies implicated LSD as a potential cause of congenital malformations, fetal wastage, and germinal chromosome damage.
In a study of human pregnancies, those exposed to illicit LSD had an elevated rate of spontaneous abortions.
This early study gets a little bit wound up in the differences between ingesting pure LSD and illicit LSD and thus obfuscates its own conclusions. So let's go onto some more interesting later studies...
hubpages.com
Of nine studies in vitro, six have indicated some degree of induced chromosomal breakage after exposure to LSD; three failed to confirm these results. The damage, when found, was generally of the chromatid type, arising during or after DNA synthesis.
The results of early chromosome studies suggested that true genetic damage might be a consequence of LSD exposure. The comprehensive evidence from studies on drosophila indicates no mutagenic effect from 0.28 to 500 microg of LSD per milliliter and a definite mutagenic effect from 2,000 to 10,000 microg/ml; this is consistent with a threshold response or a sigmoid dose-effect relation.
Circular dichroism experiments suggested that the specific mechanism of action of LSD on DNA may be a direct interaction resulting in conformational changes in the DNA helix.
Early chromosomal studies implicated LSD as a potential cause of congenital malformations, fetal wastage, and germinal chromosome damage.
In a study of human pregnancies, those exposed to illicit LSD had an elevated rate of spontaneous abortions.
This early study gets a little bit wound up in the differences between ingesting pure LSD and illicit LSD and thus obfuscates its own conclusions. So let's go onto some more interesting later studies...
hubpages.com
posted by das at 10:37 PM
